Article
Characterization of structurally defined epitopes recognized by monoclonal antibodies produced by chronic lymphocytic leukemia B cells.
Blood - 22 Oct 2009
Seiler Till, Woelfle Manuela, Yancopoulos Sophia, Catera Rosa, Li Wentian, Hatzi Katerina, Moreno Carol, Torres Marcela, Paul Santanu, Dohner Hartmut, Stilgenbauer Stephan, Kaufman Matthew S, Kolitz Jonathan E, Allen Steven L, Rai Kanti R, Chu Charles C, Chiorazzi Nicholas
Abstract excerpt
Despite a wealth of information about the structure of surface membrane immunoglobulin (smIg) on chronic lymphocytic leukemia (CLL) cells, little is known about epitopes reacting with their binding sites. Probing phage-displayed peptide libraries, we identified and characterized mimetopes for Igs...
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