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Article

Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia.

The Journal of experimental medicine - 16 Aug 2004

Messmer Bradley T, Albesiano Emilia, Efremov Dimitar G, Ghiotto Fabio, Allen Steven L, Kolitz Jonathan, Foa Robin, Damle Rajendra N, Fais Franco, Messmer Davorka, Rai Kanti R, Ferrarini Manlio, Chiorazzi Nicholas

Abstract excerpt

Previous studies suggest that the diversity of the expressed variable (V) region repertoire of the immunoglobulin (Ig)H chain of B-CLL cells is restricted. Although limited examples of marked constraint in the primary structure of the H and L chain V regions exist, the possibility that this level...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin Heavy Chains

Share to Immunoglobulin Light Chains

Share to Immunoglobulin Variable Region

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Receptors, Antigen, B-Cell

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Source

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Identifiers

PMID: 15314077
DOI: 10.1084/jem.20040544
PMCID: PMC2211936

Genes

BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15314077-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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