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Article

Fluoroquinolone resistance in Mycobacterium tuberculosis and mutations in gyrA and gyrB.

Antimicrobial agents and chemotherapy - 1 Oct 2009

Von Groll Andrea, Martin Anandi, Jureen Pontus, Hoffner Sven, Vandamme Peter, Portaels Françoise, Palomino Juan Carlos, da Silva Pedro Almeida

Abstract excerpt

This study evaluated cross-resistance of Mycobacterium tuberculosis strains to ofloxacin, moxifloxacin, and gatifloxacin and investigated the presence of mutations in gyrA and gyrB. Fluoroquinolone susceptibilities were determined for 41 M. tuberculosis strains by the proportion method on 7H11, and MICs were determined by the resazurin microtiter assay. Forty strains shared the same resistance results for the...

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Identifiers

PMID: 19687244
DOI: 10.1128/AAC.00287-09
PMCID: PMC2764174

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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