Article
Vital role for the Plasmodium actin capping protein (CP) beta‐subunit in motility of malaria sporozoites
4 Aug 2009
Abstract excerpt
Summary Successful malaria transmission from the mosquito vector to the mammalian host depends crucially on active sporozoite motility. Sporozoite locomotion and host cell invasion are driven by the parasite's own actin/myosin motor. A unique feature of this motor machinery is the presence of very short subpellicular actin filaments. Therefore, F-actin stabilizing proteins likely play a central role in parasite...
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