Article
A malaria membrane skeletal protein is essential for normal morphogenesis, motility, and infectivity of sporozoites
8 Nov 2004
Abstract excerpt
Membrane skeletons are structural elements that provide mechanical support to the plasma membrane and define cell shape. Here, we identify and characterize a putative protein component of the membrane skeleton of the malaria parasite. The protein, named PbIMC1a, is the structural orthologue of the Toxoplasma gondii inner membrane complex protein 1 (TgIMC1), a component of the membrane skeleton in tachyzoites....
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