Structure and function of a G-actin sequestering protein with a vital role in malaria oocyst development inside the mosquito vector.

Abstract excerpt

Cyclase-associated proteins (CAPs) are evolutionary conserved G-actin-binding proteins that regulate microfilament turnover. CAPs have a modular structure consisting of an N-terminal adenylate cyclase binding domain, a central proline-rich segment, and a C-terminal actin binding domain. Protozoan parasites of the phylum Apicomplexa, such as Cryptosporidium and the malaria parasite Plasmodium, express small CAP...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Actins
• Share to Cryptosporidium parvum