Article
The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly.
Nature communications - 23 Jan 2020
Pinese Mark, Lacaze Paul, Rath Emma M, Stone Andrew, Brion Marie-Jo, Ameur Adam, Nagpal Sini, Puttick Clare, Husson Shane, Degrave Dmitry, Cristina Tina Navin, Kahl Vivian F S, Statham Aaron L, Woods Robyn L, McNeil John J, Riaz Moeen, Barr Margo, Nelson Mark R, Reid Christopher M, Murray Anne M, Shah Raj C, Wolfe Rory, Atkins Joshua R, Fitzsimmons Chantel, Cairns Heath M, Green Melissa J, Carr Vaughan J, Cowley Mark J, Pickett Hilda A, James Paul A, Powell Joseph E, Kaplan Warren, Gibson Greg, Gyllensten Ulf, Cairns Murray J, McNamara Martin, Dinger Marcel E, Thomas David M
Abstract excerpt
Population health research is increasingly focused on the genetic determinants of healthy ageing, but there is no public resource of whole genome sequences and phenotype data from healthy elderly individuals. Here we describe the first release of the Medical Genome Reference Bank (MGRB), comprising whole genome sequence and phenotype of 2570 elderly Australians depleted for cancer, cardiovascular disease, and...
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