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Article

A novel nonsynonymous variant of matrix metalloproteinase-7 confers risk of liver cirrhosis.

Hepatology (Baltimore, Md.) - 1 Oct 2009

Hung Tzu-Min, Chang Shin C, Yu Wei-Hsuan, Wang Yu-Wen, Huang Cheng, Lu Shao-Chun, Lee Po-Huang, Chang Ming-Fu

Abstract excerpt

UNLABELLED: Liver cirrhosis is characterized by progressive accumulation of extracellular matrix following chronic liver injuries. In the extracellular space, the constant turnover of liver matrix is regulated by the matrix metalloproteinase (MMP) class of enzyme. To assess whether genetic variations in MMP would result in diversity of liver cirrhosis, a case-control study of 320 patients with hepatocellular...

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PMID: 19676133
DOI: 10.1002/hep.23137

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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