Article
Early effects of oral administration of esomeprazole and omeprazole on the intragastric pH.
Hepato-gastroenterology - 1 Jan 2000
Iida Hiroshi, Inamori Masahiko, Okuno Kotone, Sekino Yusuke, Sakai Eiji, Okubo Hidenori, Higurashi Takuma, Endo Hiroki, Hosono Kunihiro, Yoneda Masato, Koide Tomoko, Takahashi Hirokazu, Goto Ayumu, Kubota Kensuke, Saito Satoru, Maeda Shin, Nakajima Atsushi, Gotoh Eiji
Abstract excerpt
BACKGROUND/AIMS: The aim of our study was to investigate the inhibitory effects on gastric acid secretion of a single oral dose of a proton pump inhibitor, esomeprazole 20 mg and omeprazole 20 mg. METHODOLOGY: A total of 14 Helicobacter pylori-negative male subjects participated in this study. Intragastric pH was monitored continuously for 6 hours after a single oral dose of omeprazole 20 mg and a single oral...
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