Article
Retinoid X receptor heterodimer variants and cardiovascular risk factors.
Journal of atherosclerosis and thrombosis - 1 Aug 2009
Nohara Atsushi, Kobayashi Junji, Mabuchi Hiroshi
Abstract excerpt
Nuclear receptors are transcription factors that can be activated by specific ligands. Recent progress has shown that retinoid X receptor (RXR) and its heterodimerization partners, including peroxisome proliferator-activated receptors, regulate many important genes involved in energy homeostasis and atherosclerosis, and should be promising therapeutic targets of metabolic syndrome. RXR heterodimers regulate a...
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