Article
Comparing mutational and standing genetic variability for fitness and size in Caenorhabditis briggsae and C. elegans.
Genetics - 1 Oct 2009
Salomon Matthew P, Ostrow Dejerianne, Phillips Naomi, Blanton Dustin, Bour Whitney, Keller Thomas E, Levy Laura, Sylvestre Thamar, Upadhyay Ambuj, Baer Charles F
Abstract excerpt
The genetic variation present in a species depends on the interplay between mutation, population size, and natural selection. At mutation-(purifying) selection balance (MSB) in a large population, the standing genetic variance for a trait (VG) is predicted to be proportional to the mutational variance for the trait (VM); VM is proportional to the mutation rate for the trait. The ratio VM/VG predicts the average...
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