Article
Tubular perfusion system for chondrocyte culture and superficial zone protein expression.
Journal of biomedical materials research. Part A - 1 May 2015
Yu Li, Ferlin Kimberly M, Nguyen Bao-Ngoc B, Fisher John P
Abstract excerpt
Tissue engineering is an alternative method for articular cartilage repair. Mechanical stimulus has been found to be an important element to the healthy development of chondrocytes and maintenance of their native phenotype. To enhance nutrient transport and apply mechanical stress, we have developed a novel bioreactor, the tubular perfusion system (TPS), to culture chondrocytes in three-dimensional scaffolds. In...
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