Article
Combination of mutant EL-4 thymoma cells and EBV-infection in B lymphocyte activation a) EBV-infection of EL-4-activated lymphocytes. b) Use of EL-4 cells as feeders for lymphoblastoid cell lines.
Journal of clinical & laboratory immunology - 1 Sept 1990
Barcellini W, Borghi M O, Nicoletti F, Bonara P, Fain C, Meroni P L
Abstract excerpt
The combination of mutant EL-4 thymoma cells and Epstein-Barr virus (EBV)-infection in the activation of human B lymphocytes was studied with two approaches: a) limiting numbers of B cells were first activated by EL-4 contact in order to expand the B cell population and then infected with EBV. Re...
Topics
- B-Lymphocytes
- Cell Communication
- Cell Division
- Cell Line
- Herpesviridae Infections
- Herpesvirus 4, Human
- Humans
- Kinetics
- Lymphocyte Activation
- Mutation
- Stem Cells
- Tetradecanoylphorbol Acetate
- Thymoma
- Tumor Cells, Cultured