Article
Update on Gastrointestinal Stromal Tumors for Radiologists.
Korean journal of radiology - 1 Jan 2000
Tirumani Sree Harsha, Baheti Akshay D, Tirumani Harika, O'Neill Ailbhe, Jagannathan Jyothi P
Abstract excerpt
The management of gastrointestinal stromal tumors (GISTs) has evolved significantly in the last two decades due to better understanding of their biologic behavior as well as development of molecular targeted therapies. GISTs with exon 11 mutation respond to imatinib whereas GISTs with exon 9 or succinate dehydrogenase subunit mutations do not. Risk stratification models have enabled stratifying GISTs according to...
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