Article
Association of the LRP1 gene and cognitive performance with amnestic mild cognitive impairment in elderly Chinese.
International psychogeriatrics - 1 Dec 2009
Shi Yong M, Zhou Hong, Zhang Zhi J, Yu Hui, Bai Feng, Yuan Yong G, Deng Ling L, Jia Jian P
Abstract excerpt
BACKGROUND: The genetic region coding for low-density lipoprotein receptor-related protein1 (LRP1) is considered an intriguing susceptibility locus for Alzheimer's disease (AD). Amnestic mild cognitive impairment (aMCI) is characterized by episodic memory impairment and represents the prodromal stage of AD. Our aim in this study is to investigate the relationship between LRP1 genetic variation and aMCI, and the...
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