Identification of apolipoprotein N-acyltransferase (Lnt) in mycobacteria.

Abstract excerpt

Lipoproteins of Gram-negative and Gram-positive bacteria carry a thioether-bound diacylglycerol but differ by a fatty acid amide bound to the alpha-amino group of the universally conserved cysteine. In Escherichia coli the N-terminal acylation is catalyzed by the N-acyltransferase Lnt. Using E. coli Lnt as a query in a BLASTp search, we identified putative lnt genes also in Gram-positive mycobacteria. The...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Actinobacteria
• Share to Acylation
• Share to Acyltransferases