Article
Structural insights into lipoprotein N-acylation by Escherichia coli apolipoprotein N-acyltransferase.
Proceedings of the National Academy of Sciences of the United States of America - 25 Jul 2017
Noland Cameron L, Kattke Michele D, Diao Jingyu, Gloor Susan L, Pantua Homer, Reichelt Mike, Katakam Anand K, Yan Donghong, Kang Jing, Zilberleyb Inna, Xu Min, Kapadia Sharookh B, Murray Jeremy M
Abstract excerpt
Gram-negative bacteria express a diverse array of lipoproteins that are essential for various aspects of cell growth and virulence, including nutrient uptake, signal transduction, adhesion, conjugation, sporulation, and outer membrane protein folding. Lipoprotein maturation requires the sequential activity of three enzymes that are embedded in the cytoplasmic membrane. First, phosphatidylglycerol:prolipoprotein...
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