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Whole genome sequencing of a single Bos taurus animal for single nucleotide polymorphism discovery.

Genome biology - 1 Jan 2009

Eck Sebastian H, Benet-Pagès Anna, Flisikowski Krzysztof, Meitinger Thomas, Fries Ruedi, Strom Tim M

Abstract excerpt

BACKGROUND: The majority of the 2 million bovine single nucleotide polymorphisms (SNPs) currently available in dbSNP have been identified in a single breed, Hereford cattle, during the bovine genome project. In an attempt to evaluate the variance of a second breed, we have produced a whole genome sequence at low coverage of a single Fleckvieh bull. RESULTS: We generated 24 gigabases of sequence, mainly using...

Topics

Animals
Cattle
Female
Genome
INDEL Mutation
Male
Polymorphism, Single Nucleotide
Sequence Analysis, DNA

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 19660108
DOI: 10.1186/gb-2009-10-8-r82
PMCID: PMC2745763

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