Article
Identification and annotation of breed-specific single nucleotide polymorphisms in Bos taurus genomes.
PloS one - 1 Jan 2018
Czech Bartosz, Frąszczak Magdalena, Mielczarek Magda, Szyda Joanna
Abstract excerpt
In Bos taurus the universality of the reference genome is biased towards genetic variation represented by only two related individuals representing the same Hereford breed. Therefore, results of genetic analyses based on this reference may not be reliable. The 1000 Bull Genomes resource allows for identification of breed-specific polymorphisms and for the construction of breed-specific reference genomes....
Topics
- Animals
- Breeding
- Cattle
- Gene Frequency
- Genetic Variation
- Genome
- Genotype
- Male
- Polymorphism, Single Nucleotide
- Whole Genome Sequencing