Article
Assessment of the genomic variation in a cattle population by re-sequencing of key animals at low to medium coverage.
BMC genomics - 4 Jul 2013
Jansen Sandra, Aigner Bernhard, Pausch Hubert, Wysocki Michal, Eck Sebastian, Benet-Pagès Anna, Graf Elisabeth, Wieland Thomas, Strom Tim M, Meitinger Thomas, Fries Ruedi
Abstract excerpt
BACKGROUND: Genome- and population-wide re-sequencing would allow for most efficient detection of causal trait variants. However, despite a strong decrease of costs for next-generation sequencing in the last few years, re-sequencing of large numbers of individuals is not yet affordable. We therefore resorted to re-sequencing of a limited number of bovine animals selected to explain a major proportion of the...
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