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Article

Stem-Like Ovarian Cancer Cells Can Serve as Tumor Vascular Progenitors

5 Aug 2009

Abstract excerpt

Neovascularization is required for solid tumor maintenance, progression, and metastasis. The most described contribution of cancer cells in tumor neovascularization is the secretion of factors, which attract various cell types to establish a microenvironment that promotes blood vessel formation. The cancer stem cell hypothesis suggests that tumors are composed of cells that may share the differentiation capacity...

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PMID: 19658191
DOI: 10.1002/stem.191

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