Article
Mad is required for wingless signaling in wing development and segment patterning in Drosophila.
PloS one - 6 Aug 2009
Eivers Edward, Fuentealba Luis C, Sander Veronika, Clemens James C, Hartnett Lori, De Robertis E M
Abstract excerpt
A key question in developmental biology is how growth factor signals are integrated to generate pattern. In this study we investigated the integration of the Drosophila BMP and Wingless/GSK3 signaling pathways via phosphorylations of the transcription factor Mad. Wingless was found to regulate th...
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