Human telomeres that contain (CTAGGG)n repeats show replication dependent instability in somatic cells and the male germline.

Abstract excerpt

A number of different processes that impact on telomere length dynamics have been identified but factors that affect the turnover of repeats located proximally within the telomeric DNA are poorly defined. We have identified a particular repeat type (CTAGGG) that is associated with an extraordinarily high mutation rate (20% per gamete) in the male germline. The mutation rate is affected by the length and sequence...

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