Article
Telomere instability in the male germline.
Human molecular genetics - 1 Jan 2006
Baird Duncan M, Britt-Compton Bethan, Rowson Jan, Amso Nazar N, Gregory Linda, Kipling David
Abstract excerpt
Telomeres play a key role in upholding the integrity of the genome, and telomerase expression in spermatogonial stem cells is responsible for the maintenance of telomere length in the human male germline. We have previously described extensive allelic variation in somatic cell telomere length that is set in the zygote, the ultimate source of which may be the germline. This implies that despite telomerase...
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