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Article

Energy intake and energy expenditure among children with polymorphisms of the melanocortin-3 receptor.

The American journal of clinical nutrition - 1 Oct 2009

Savastano David M, Tanofsky-Kraff Marian, Han Joan C, Ning Cong, Sorg Rachael A, Roza Caroline A, Wolkoff Laura E, Anandalingam Kavitha, Jefferson-George Kyra S, Figueroa Roberto E, Sanford Ethan L, Brady Sheila, Kozlosky Merel, Schoeller Dale A, Yanovski Jack A

Abstract excerpt

BACKGROUND: Homozygosity for 2 protein-altering polymorphisms in the melanocortin-3 receptor gene (MC3R) coding sequence, C17A and G241A, has been reported to be associated with an obesity phenotype in children, yet how these polymorphisms affect energy homeostasis is unknown. Association between adult body weight and +2138InsCAGACC, another variant in the 3' untranslated region of MC3R, has also been described....

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Identifiers

PMID: 19656839
DOI: 10.3945/ajcn.2009.27537
PMCID: PMC2744620

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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