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Article

Population genomics in a disease targeted primary cell model.

Genome research - 1 Nov 2009

Grundberg Elin, Kwan Tony, Ge Bing, Lam Kevin C L, Koka Vonda, Kindmark Andreas, Mallmin Hans, Dias Joana, Verlaan Dominique J, Ouimet Manon, Sinnett Daniel, Rivadeneira Fernando, Estrada Karol, Hofman Albert, van Meurs Joyce M, Uitterlinden André, Beaulieu Patrick, Graziani Alexandru, Harmsen Eef, Ljunggren Osten, Ohlsson Claes, Mellström Dan, Karlsson Magnus K, Nilsson Olle, Pastinen Tomi

Abstract excerpt

The common genetic variants associated with complex traits typically lie in noncoding DNA and may alter gene regulation in a cell type-specific manner. Consequently, the choice of tissue or cell model in the dissection of disease associations is important. We carried out an expression quantitative trait loci (eQTL) study of primary human osteoblasts (HOb) derived from 95 unrelated donors of Swedish origin, each...

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Identifiers

PMID: 19654370
DOI: 10.1101/gr.095224.109
PMCID: PMC2775606

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SRR
MSH3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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