Article
Characterization of single-nucleotide polymorphisms relevant to inflammatory bowel disease in commonly used gastrointestinal cell lines.
Inflammatory bowel diseases - 1 Feb 2010
Huebner Claudia, Petermann Ivonne, Lam Wen Jiun, Shelling Andrew N, Ferguson Lynnette R
Abstract excerpt
BACKGROUND: The era of genome-wide association studies (GWAS) has led to the identification of many inflammatory bowel disease (IBD)-associated single-nucleotide polymorphisms (SNPs) with unknown function. The next step would be to identify the functional consequences of these polymorphisms in order to target them efficiently for therapeutic purposes. One way to study this type of genetic variation is the use of...
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