Article
The neurotransmitter VIP expands the pool of symmetrically dividing postnatal dentate gyrus precursors via VPAC2 receptors or directs them toward a neuronal fate via VPAC1 receptors.
Stem cells (Dayton, Ohio) - 1 Oct 2009
Zaben Malik, Sheward W John, Shtaya Anan, Abbosh Christopher, Harmar Anthony J, Pringle Ashley K, Gray William P
Abstract excerpt
The controlled production of neurons in the postnatal dentate gyrus and throughout life is important for hippocampal learning and memory. The mechanisms underlying the necessary coupling of neuronal activity to neural stem/progenitor cell (NSPC) function remain poorly understood. Within the dentate subgranular stem cell niche, local interneurons appear to play an important part in this excitation-neurogenesis...
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