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Article

Influence of the polymorphisms of the alpha-major regulatory element HS-40 on in vitro gene expression.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Sept 2009

Ribeiro D M, Zaccariotto T R, Santos M N N, Costa F F, Sonati M F

Abstract excerpt

The alpha-MRE is the major regulatory element responsible for the expression of human alpha-like globin genes. It is genetically polymorphic, and six different haplotypes, named A to F, have been identified in some population groups from Europe, Africa and Asia and in native Indians from two Brazilian Indian tribes. Most of the mutations that constitute the alpha-MRE haplotypes are located in flanking sequences...

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PMID: 19649390
DOI: 10.1590/s0100-879x2009005000014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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