Article
A hypothesis for the initiation of COPD.
The European respiratory journal - 1 Aug 2009
Tzortzaki E G, Siafakas N M
Abstract excerpt
Chronic obstructive pulmonary disease (COPD) is generally thought to depend on an aberrant immune response to a noxious or infectious agent, which may cause chronic inflammation. However, the initiation of this abnormal response is not fully understood. Here, we propose a new hypothesis for the beginning of COPD, that the immune response to inhaled agents, mainly cigarette smoke, is directed toward the airway...
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