Article
1. COPD pathogenesis from the viewpoint of risk factors.
Internal medicine (Tokyo, Japan) - 1 Jan 2007
Teramoto Shinji
Abstract excerpt
Chronic obstructive pulmonary disease (COPD) is characterized by irreversible airflow limitation in the lungs. Smoking is one of the amongst major risk factors for the development of COPD. Environmental pollution, age, and airway hyperreactivity are also the risk factors. The protease-antiprotease imbalance and the oxidant-antioxidant imbalance cause airway inflammation and destruction. The genes related to these...
Topics
- Adenovirus Infections, Human
- Genetic Predisposition to Disease
- Humans
- Oxidative Stress
- Pulmonary Disease, Chronic Obstructive
- Respiratory Tract Infections
- Risk Factors
- Smoking