Estimation of Genetic Admixture Proportions via Haplotypes

Abstract excerpt

Estimation of ethnic admixture is essential for creating personal genealogies, studying human history, and conducting genome-wide association studies (GWAS). Three methods exist for estimating admixture coefficients. The frequentist approach directly maximizes the binomial loglikelihood. The Bayesian approach adds a reasonable prior and samples the posterior distribution. Finally, the nonparametric approach decomp...

Topics

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• Algorithms
• Computer Simulation
• Exome
• Genome, Human
• HapMap Project
• Likelihood Functions
• Population Groups
• Software

Identifiers and source

Literature Corpus work

bec2666a-9043-5c84-a102-b6d8a6eb8bd1

DOI

10.1101/2023.09.22.559067