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Proteomic Analysis of Mouse Oocytes Reveals 28 Candidate Factors of the “Reprogrammome”

24 Feb 2011

Abstract excerpt

The oocyte is the only cell of the body that can reprogram transplanted somatic nuclei and sets the gold standard for all reprogramming methods. Therefore, an in-depth characterization of its proteome holds promise to advance our understanding of reprogramming and germ cell biology. To date, limitations on oocyte numbers and proteomic technology have impeded this task, and the search for reprogramming factors has...

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PMID: 21344949
DOI: 10.1021/pr100706k

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