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Article

Semaphorin 3A levels in vascular and nonvascular phenotypes in systemic sclerosis.

Laboratory medicine - 2 Nov 2023

Kayaalp Mehmet, Erden Abdulsamet, Apaydin Hakan, Güven Serdar Can, Armağan Berkan, Cağlayan Kayaalp Merve, Andac Uzdogan Esma, Ala Enli Şeymanur, Omma Ahmet, Kucuksahin Orhan

Abstract excerpt

OBJECTIVE: Semaphorin 3A (Sema3A) plays a regulatory role in immune responses. The aim of this study was to evaluate Sema3A levels in patients with systemic sclerosis (SSc), especially in major vascular involvements such as digital ulcer (DU), scleroderma renal crisis (SRC), pulmonary arterial hypertension (PAH), and to compare Sema3A level with SSc disease activity. METHODS: In SSc patients, patients with DU,...

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PMID: 37100766
DOI: 10.1093/labmed/lmad019

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