Article
IgM antiphospholipid antibodies are associated with a microvascular phenotype in antiphospholipid syndrome.
Advances in rheumatology (London, England) - 11 Jun 2026
Signorelli Flavio, de Andrade Lopes Fernanda Oliveira, Gomes Andreia Coimbra Sousa, Balbi Gustavo Guimarães Moreira, Cecchi Irene, Radin Massimo, Sciascia Savino, Andrade Danieli Castro Oliveira de
Abstract excerpt
BACKGROUND: The clinical significance of IgM antiphospholipid antibodies (aPL) in antiphospholipid syndrome (APS) remains uncertain, while lupus anticoagulant is a well-established marker for thrombotic risk. METHODS: The objective of the study is to evaluate the impact of IgM aPL on the clinical phenotype of primary APS (PAPS). In this retrospective multicenter study, patients meeting updated Sapporo...
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