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Article

Nucleotide substitutions of hepatitis E virus genomes associated with fulminant hepatitis and disease severity.

The Tohoku journal of experimental medicine - 1 Aug 2009

Inoue Jun, Takahashi Masaharu, Mizuo Hitoshi, Suzuki Kazuyuki, Aikawa Tatsuya, Shimosegawa Tooru, Okamoto Hiroaki

Abstract excerpt

Hepatitis E virus (HEV) is one of the causative agents of acute or fulminant hepatitis. Viral factors may play a role in the pathogenesis of fulminant hepatitis E. We aimed to investigate the nucleotide substitutions of the HEV genome affecting the severity of hepatitis E. The comparison of 28 re...

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Identifiers

PMID: 19638731
DOI: 10.1620/tjem.218.279

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19638731-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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