Article
The pleiotropic cell separation mutation spl1-1 is a nucleotide substitution in the internal promoter of the proline tRNACGG gene of Schizosaccharomyces pombe.
Current genetics - 1 Oct 2009
Miklos Ida, Ludanyi Katalin, Sipiczki Matthias
Abstract excerpt
spl1-1 was originally identified as a spontaneous mutation genetically interacting with sep1-1 and cdc4-8 in producing multinucleate syncytia. This study shows that it is allelic with the proline-tRNA(CGG) gene SPATRNAPRO.02. Its nucleotide sequence contains a C-->T substitution in the region corresponding to the B-box of the putative intragenic promoter and the TpsiC loop of the mature tRNA. The substitution...
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