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Article

Tip links in hair cells: molecular composition and role in hearing loss

15 Sept 2009

Abstract excerpt

PURPOSE OF REVIEW: Tip links are thought to be an essential element of the mechanoelectrical transduction (MET) apparatus in sensory hair cells of the inner ear. The molecules that form tip links have recently been identified, and the analysis of their properties has not only changed our view of MET but also suggests that tip-link defects can cause hearing loss. RECENT FINDINGS: Structural, histological and...

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Identifiers

PMID: 19633555
DOI: 10.1097/moo.0b013e3283303472

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Tip links in hair cells: molecular composition and role in hearing lossPMID 19633555Read ↗

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The CD2 isoform of protocadherin-15 is an essential component of the tip-link complex in mature auditory hair cells.Semantic proximity Read ↗

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