Article
Hair cells, plasma membrane Ca²⁺ ATPase and deafness.
The international journal of biochemistry & cell biology - 1 May 2012
Giacomello Marta, De Mario Agnese, Primerano Simona, Brini Marisa, Carafoli Ernesto
Abstract excerpt
Hearing relies on the ability of the inner ear to convert sound waves into electrical signals. The main actors in this process are hair cells. Their stereocilia contain a number of specific proteins and a scaffold of actin molecules. They are organized in bundles by tip-link filaments composed of cadherin 23 and protocadherin 15. The bundle is deflected by sound waves leading to the opening of...
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