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Article

Broad-host-range gyrase A gene probe.

Antimicrobial agents and chemotherapy - 1 Oct 1990

Robillard N J

Abstract excerpt

The Escherichia coli gyrase A gene was cloned in the broad-host-range cosmid vector pLA2917. The resulting plasmid, pNJR3-2, conferred quinolone susceptibility on a gyrA mutant of E. coli. To analyze the expression of this E. coli gene in Pseudomonas aeruginosa, pNJR3-2 or pLA2917 was mobilized via conjugation into P. aeruginosa PAO2 and several well-characterized quinolone-resistant mutants of this strain. The...

Topics

Anti-Bacterial Agents
DNA Topoisomerases, Type II
Escherichia coli
Gene Expression Regulation, Bacterial
Gene Expression Regulation, Enzymologic
Genes, Bacterial
Genetic Vectors
Genotype
Microbial Sensitivity Tests
Phenotype
Plasmids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pseudomonas aeruginosa

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Identifiers

PMID: 1963286
DOI: 10.1128/AAC.34.10.1889
PMCID: PMC171960

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1963286-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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