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Article

Rapid identification of HBB gene mutations by high-resolution melting analysis.

Clinical biochemistry - 1 Nov 2009

Shih Hung-Chang, Er Tze-Kiong, Chang Tien-Jye, Chang Ya-Sian, Liu Ta-Chih, Chang Jan-Gowth

Abstract excerpt

OBJECTIVE: This study was undertaken to identify HBB gene mutation. DESIGN AND METHODS: Herein we evaluated high-resolution melting analysis in the identification of HBB mutations. RESULTS: We have successfully established a diagnostic strategy for identifying HBB gene mutations including c.-78A>G, c.-79A>G, c.2T>G, c.79_80insT, c.84_85insC, c.123_124insT, c.125_128delTCTT, c.130 G>T, c.170G>A, c.216_217ins A and...

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PMID: 19631632
DOI: 10.1016/j.clinbiochem.2009.07.017

Genes

HBB

Variants

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