Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Scanning for α-Hemoglobin Variants by High-Resolution Melting Analysis.

Journal of clinical laboratory analysis - 1 Sept 2016

Yimniam Walaiporn, Jindadamrongwech Sumalee

Abstract excerpt

BACKGROUND: Definitive detection of hemoglobin (Hb) variants requires DNA sequencing. High-resolution melting (HRM) analysis of polymerase chain reaction (PCR) amplicons was applied to detect and discriminate among uncommon α-Hb variants found in Thailand. METHODS: Uncommon suspected α-Hb variants observed in Hb typing were identified by sequencing of DNA from whole blood samples. Three pairs of PCR primers...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha-Globins
Share to Base Sequence
Share to HBA1 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Nucleic Acid Denaturation

Share to Polymerase Chain Reaction

Share to Sequence Analysis, DNA

Share to Thailand

Source

Open in PubMed Open full text

Identifiers

PMID: 26892340
DOI: 10.1002/jcla.21914
PMCID: PMC6807199

Genes

HBA1
HBA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Scanning for α-Hemoglobin Variants by High-Resolution Melting Analysis.PMID 26892340Read ↗

Genotyping of beta thalassemia trait by high-resolution DNA melting analysis.Semantic proximity Read ↗

Development of a High Resolution Melting Curve Analysis for the Detection of Hemoglobin δ-Chain Variants in Thailand and Identification of Hb A2-Walsgrave [codon 52 (GAT>CAT), Asp→His; HBD:c.157G>C] in a Pregnant Woman from Southern Thailand.Semantic proximity Read ↗

Screening for mutations in the α-globin genes leading to abnormal hemoglobin variants with high resolution melting analysis.Semantic proximity Read ↗

Detection of Hb H disease genotypes common in northern Thailand by quantitative real-time polymerase chain reaction and high resolution melting analyses.Semantic proximity Read ↗

High resolution melting analytical platform for rapid prenatal and postnatal diagnosis of β-thalassemia common among Southeast Asian population.Semantic proximity Read ↗

Simultaneous Characterization of Deletional and Nondeletional Globin Gene Mutations by Multiplex Real-Time-Polymerase Chain Reaction and High-Resolution Melting Curve Analysis.Semantic proximity Read ↗

Molecular characterization of G6PD mutations identifies new mutations and a high frequency of intronic variants in Thai females.Semantic proximity Read ↗

High-resolution melting analysis for prenatal diagnosis of beta-thalassemia in northern ThailandSemantic proximity Read ↗

One-step amplification refractory mutation system-PCR/high-resolution melting curve assay for carrier detection of red blood cell membranopathy caused by common SPTB mutations.Semantic proximity Read ↗

Rapid identification of HBB gene mutations by high-resolution melting analysis.Semantic proximity Read ↗

Detection of α-thalassemia-1 Southeast Asian and Thai type deletions and β-thalassemia 3.5-kb deletion by single-tube multiplex real-time PCR with SYBR Green1 and high-resolution melting analysis.Semantic proximity Read ↗

Single-tube multiplex real-time PCR with EvaGreen and high-resolution melting analysis for diagnosis of α0-thalassemia--SEA,--THAI, and--CR type deletionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.