Article
Influence of the Pro12Ala polymorphism of PPAR-gamma on age at onset and sRAGE levels in Alzheimer's disease.
Brain research - 29 Sept 2009
Yao Lifen, Li Keshen, Zhang Liming, Yao Songpo, Piao Zhongyuan, Song Lin
Abstract excerpt
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) has been described to have a role in the modulation of various genes involved in Abeta homeostasis, inflammation, and energy metabolism, making it a candidate gene for risk of Alzheimer's disease (AD). A functional polymorphism in exon...
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