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Article

Association of the PPARgamma gene polymorphism Pro12Ala with delayed onset of multiple sclerosis.

Neuroscience letters - 2 Jan 2009

Klotz Luisa, Schmidt Stephan, Heun Reinhard, Klockgether Thomas, Kölsch Heike

Abstract excerpt

PPARs belong to a receptor family of ligand-activated transcription factors involved in the regulation of inflammation. A crucial role both for PPARgamma and for PPARalpha for the regulation of autoimmunity has been clearly demonstrated, as receptor agonists had beneficial effects on several CD4(+) T cell mediated autoimmune diseases including experimental autoimmune encephalomyelitis (EAE), the animal model of...

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Source

Identifiers

PMID: 18977277
DOI: 10.1016/j.neulet.2008.10.066

Genes

PPARG
PPARA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Association of the PPARgamma gene polymorphism Pro12Ala with delayed onset of multiple sclerosis.PMID 18977277Read ↗

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Association of peroxisome proliferator-activated receptor gamma polymorphisms with inflammatory bowel disease in a Hungarian cohort.Semantic proximity Read ↗

Association of the Pro12Ala polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study.Semantic proximity Read ↗

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