Article
Tropomyosin: function follows structure.
Advances in experimental medicine and biology - 1 Jan 2008
Hitchcock-DeGregori Sarah E
Abstract excerpt
Tropomyosin is known as the archetypal coiled coil, being the first to be sequenced and modeled. Studies of the structure and dynamics of tropomyosin, accompanied by biochemical and biophysical analyses of tropomyosin, mutants and model peptides, have revealed the complexity and subtleties required for tropomyosin function. Interruptions in the canonical coiled coil allow for bends and regions of local...
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