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Article

IGF2R polymorphisms and risk of esophageal and gastric adenocarcinomas.

International journal of cancer - 1 Dec 2009

Hoyo Cathrine, Schildkraut Joellen M, Murphy Susan K, Chow Wong-Ho, Vaughan Thomas L, Risch Harvey, Marks Jeffrey R, Jirtle Randy L, Calingaert Brian, Calingeart Brian, Mayne Susan, Fraumeni Joseph, Gammon Marilie D

Abstract excerpt

The mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) encodes a protein that plays a critical role in tumor suppression, in part by modulating bioavailability of a potent mitogen, insulin-like growth factor-2 (IGF2). We tested the hypothesis that the common nonsynonymous genetic variants in M6P/IGF2R c.901C > G (Leu > Val) in exon 6 and c.5002G > A (Gly > Arg) in exon 34 are associated with...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19626700
DOI: 10.1002/ijc.24623
PMCID: PMC3008656

Genes

IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

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IGF2R polymorphisms and risk of esophageal and gastric adenocarcinomas.PMID 19626700Read ↗

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IGF2R genetic variants, circulating IGF2 concentrations and colon cancer risk in African Americans and Whites.Semantic proximity Read ↗

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