Article
Dynamic changes of HBV quasispecies and deletion patterns in a chronic hepatitis B patient.
Journal of medical virology - 1 Sept 2009
Ji Fen, Zhou Li, Ma Sufang, Li Feifei, Ding Huiguo, Zeng Changqing
Abstract excerpt
Hepatitis B virus (HBV) infection is a dynamic process during which molecular variants are selected continuously to adapt to changes. In addition to drug resistant mutations, sequential antiviral therapy may also lead to the selection of deleted mutants. To investigate this process, the following samples were collected from a patient who failed lamivudine therapy and then was switched to adefovir dipivoxil. HBV...
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