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Article

Knockdown of autophagy-related gene decreases the production of infectious Hepatitis C virus particles

1 Oct 2009

Abstract excerpt

Hepatitis C virus (HCV) is a positive-strand RNA virus, and classified within the Flaviridae family. Atg7-knockdown decreases the amount of HCV replicon RNA, when HCV JFH1 RNA and HCV subgenomic replicon are transfected into Huh7.5 cells. However, when infectious naive HCV particles are directly infected into Huh7.5.1 cells, it is still unclear whether Atg7-knockdown decreases the production of intracellular...

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PMID: 19625776
DOI: 10.4161/auto.5.7.9243

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