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Article

Autophagy proteins promote hepatitis C virus replication

16 Nov 2009

Abstract excerpt

Autophagy is a fundamental process for anti-viral defense. Not surprisingly, viruses have developed strategies to subvert or use autophagy for their own benefit. In cell culture, autophagy proteins are proviral factors that favor initiation of hepatitis C virus (HCV) infection. Autophagy proteins are required for translation of incoming viral RNA. We propose that autophagy factors might support the delivery of...

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PMID: 19844160
DOI: 10.4161/auto.5.8.10219

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