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Article

Hepatitis C virus genotype 1a growth and induction of autophagy.

Journal of virology - 1 Mar 2008

Ait-Goughoulte Malika, Kanda Tatsuo, Meyer Keith, Ryerse Jan S, Ray Ratna B, Ray Ranjit

Abstract excerpt

We have previously reported that immortalized human hepatocytes (IHH) support the generation of infectious hepatitis C virus (HCV) genotype 1a (clone H77). In the present study, we have investigated the growth of HCV genotype 1a (clone H77) through serial passages and accompanying changes in IHH in response to infection. Eleven serial passages of HCV genotype 1a (clone H77) in IHH were completed. Virus...

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Identifiers

PMID: 18077704
DOI: 10.1128/JVI.02093-07
PMCID: PMC2258951

Genes

IHH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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